Timo Palosuo Selected Research

Latex Hypersensitivity (Latex Allergy)

5/2011	Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.
11/2005	Cutaneous, but not airway, latex exposure induces allergic lung inflammation and airway hyperreactivity in mice.
3/2005	Isolated hevein-like domains, but not 31-kd endochitinases, are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit syndrome.
2/2004	Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex allergy by comutation of six amino acid residues on the conformational IgE epitopes.
4/2003	Epicutaneous natural rubber latex sensitization induces T helper 2-type dermatitis and strong prohevein-specific IgE response.
10/2002	Recent developments in latex allergy.
8/2002	Long-term outcome of 160 adult patients with natural rubber latex allergy.

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Timo Palosuo Research Topics

Disease

7	Latex Hypersensitivity (Latex Allergy) 05/2011 - 08/2002
7	Hypersensitivity (Allergy) 01/2011 - 05/2002
5	Inflammation (Inflammations) 12/2004 - 03/2002
4	Coronary Disease (Coronary Heart Disease) 12/2004 - 01/2002
4	Periodontitis 11/2004 - 12/2002
3	Rheumatoid Arthritis 10/2012 - 09/2003
3	Asthma (Bronchial Asthma) 05/2011 - 10/2002
2	Pneumonia (Pneumonitis) 05/2011 - 11/2005
2	Food Hypersensitivity (Food Allergy) 08/2008 - 12/2006
2	Arthritis (Polyarthritis) 11/2007 - 09/2003
2	Acute Coronary Syndrome 09/2005 - 10/2004
2	Persistent Infection 12/2004 - 05/2003
2	Infections 12/2004 - 03/2002
2	Dermatitis 10/2004 - 04/2003
2	Eczema 10/2004 - 08/2002
2	Contact Dermatitis (Eczema, Contact) 10/2004 - 04/2003
2	Chlamydophila Infections 05/2003 - 03/2002
1	Bronchial Hyperreactivity 05/2011
1	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 05/2011
1	Atopic Dermatitis (Atopic Eczema) 08/2008
1	Diarrhea 12/2006
1	Rupture 09/2005
1	Chest Pain (Chest Pains) 09/2005
1	Herpes Simplex 12/2004
1	Anaphylaxis (Anaphylactic Shock) 10/2004
1	Atherosclerosis 05/2003
1	Chronic Periodontitis 12/2002
1	Chronic Bronchitis 10/2002
1	Abdominal Obesity 10/2002
1	Spinal Dysraphism (Spina Bifida) 05/2002
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2002
1	Mannose-Binding Protein Deficiency 01/2002

Drug/Important Bio-Agent (IBA)

9	AllergensIBA 05/2011 - 05/2002
8	LatexIBA 05/2011 - 05/2002
6	AntibodiesIBA 10/2012 - 03/2002
6	Rubber (Elastica)IBA 05/2011 - 05/2002
6	Proteins (Proteins, Gene)FDA Link 01/2011 - 10/2002
6	Immunoglobulin E (IgE)IBA 08/2008 - 04/2003
4	C-Reactive ProteinIBA 12/2004 - 10/2002
2	Peptides (Polypeptides)IBA 10/2012 - 11/2007
2	CollagenIBA 10/2012 - 11/2007
2	CytokinesIBA 05/2011 - 09/2003
2	Chaperonin 60IBA 05/2003 - 03/2002
2	Fibrinogen (Factor I)FDA Link 12/2002 - 10/2002
1	VimentinIBA 10/2012
1	CytosineIBA 05/2011
1	GuanosineIBA 05/2011
1	Methacholine Chloride (Methacholine)FDA Link 05/2011
1	Phosphates (Orthophosphate)IBA 05/2011
1	PowdersIBA 01/2011
1	AlbuminsIBA 08/2008
1	AutoantibodiesIBA 11/2007
1	Collagen Type II (Type II Collagen)IBA 11/2007
1	Rheumatoid FactorIBA 11/2007
1	OvalbuminIBA 12/2006
1	Peptide Hydrolases (Proteases)FDA Link 09/2005
1	Matrix Metalloproteinases (MMPs)IBA 09/2005
1	Tryptases (Tryptase)IBA 09/2005
1	IronIBA 12/2004
1	oxidized low density lipoproteinIBA 11/2004
1	LipopolysaccharidesIBA 11/2004
1	Interleukin-2 Receptors (IL 2 Receptor)IBA 10/2004
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 10/2004
1	SolutionsIBA 10/2004
1	heveinIBA 02/2004
1	Amino Acids FDA Link 02/2004
1	EpitopesIBA 02/2004
1	HDL LipoproteinsIBA 01/2004
1	CholesterolIBA 01/2004
1	Interferon-gamma (Interferon, gamma)IBA 09/2003
1	Interleukin-4 (Interleukin 4)IBA 09/2003
1	Biomarkers (Surrogate Marker)IBA 09/2003
1	Chemokine ReceptorsIBA 09/2003
1	Immunoglobulin G (IgG)IBA 07/2003
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 10/2002
1	Recombinant DNA (Recombinant DNA Research)IBA 10/2002
1	L 644711 (B-3(+))IBA 05/2002
1	Immunoglobulin A (IgA)IBA 03/2002
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2002

Therapy/Procedure

2	Aftercare (After-Treatment) 11/2004 - 12/2002
1	Injections 05/2011
1	Immunotherapy 02/2004
1	Protective Gloves 08/2002